Quarterly report pursuant to Section 13 or 15(d)

STOCKHOLDERS' EQUITY (Details Narrative)

v3.22.1
STOCKHOLDERS' EQUITY (Details Narrative) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended
Feb. 15, 2022
Jul. 11, 2021
Mar. 26, 2021
Feb. 02, 2021
Jan. 19, 2021
Jun. 02, 2020
Apr. 04, 2020
Jan. 28, 2020
Jan. 24, 2019
Jul. 02, 2018
Jan. 03, 2017
Jan. 31, 2021
Mar. 31, 2022
Mar. 31, 2021
Jul. 31, 2021
Dec. 31, 2021
Nov. 20, 2020
Class of Stock [Line Items]                                  
Common stock, shares authorized                         200,000,000     200,000,000  
Preferred stock, shares authorized                         4,268     4,268  
Preferred stock par value $ 1,000                       $ 0.0001     $ 0.0001  
Number of shares issued   306,866                              
Stock issued during the period, value                           $ 39,074,390      
Proceeds from issuance of stock $ 4,205,000 $ 36,259,050                              
Proceeds from issuance of common stock                         $ 4,205,000 39,911,415      
Number of warrants issued                         133     133  
Exercise price of warrants $ 37.65 $ 121.5                              
Warrants to purchase common stock   153,433                              
Proceeds from warrants exercise                         $ 0 5,408,540      
Warrant offering price   $ 130.35                              
Cash fee equal to gross proceeds 7.00% 7.00%                              
Management fee equal to gross proceeds 0.50% 0.50%                              
Placement agent expenses   $ 25,000                              
Legal fee   50,000                              
Clearing fee   $ 15,950                              
Description for market capitalization   common stock (which represents 6.0% of the shares sold to investors in the offering) at an exercise price equal to 125% of the offering price in the offering, or $162.94 (the “Placement Agent Warrants”). The Placement Agent Warrants are immediately exercisable until the fifth anniversary of the commencement of sales of the offering                              
Offering price   $ 162.94                              
Aggregate preferred stock issued $ 5,000,000                                
Total issuance costs 795,000                                
Initial fair value of warrants $ 2,646,135                       2,646,135 0      
Warrant issuance costs                         275,130 $ 0      
Warrant [Member]                                  
Class of Stock [Line Items]                                  
Proceeds from warrants exercise   $ 40,000,000                              
2021 Offering Warrants [Member] | Warrant [Member]                                  
Class of Stock [Line Items]                                  
Financial liabilities at fair value                         1,589,284     $ 1,589,284  
Placement Agent Warrants [Member] | Warrant [Member]                                  
Class of Stock [Line Items]                                  
Financial liabilities at fair value                         4,801,929     $ 4,801,929  
2016 Equity Incentive Plan [Member]                                  
Class of Stock [Line Items]                                  
Unrecognized compensation expense                         0        
2018 Equity Incentive Plan [Member]                                  
Class of Stock [Line Items]                                  
Unrecognized compensation expense                         $ 0        
2018 Equity Incentive Plan [Member] | January 1, 2021 [Member]                                  
Class of Stock [Line Items]                                  
Restricted stock units vesting term percentage             33.00%                    
2018 Equity Incentive Plan [Member] | January 1, 2022 [Member]                                  
Class of Stock [Line Items]                                  
Restricted stock units vesting term percentage             34.00%                    
2018 Equity Incentive Plan [Member] | January 1, 2023 [Member]                                  
Class of Stock [Line Items]                                  
Restricted stock units vesting term percentage             33.00%                    
At The Market Offering Agreement [Member]                                  
Class of Stock [Line Items]                                  
Number of shares issued                       99,748     125,708    
Proceeds from issuance of stock         $ 8,721,746                        
Proceeds from issuance of common stock                       $ 16,200,000          
Second At The Market Offering Agreement [Member]                                  
Class of Stock [Line Items]                                  
Proceeds from issuance of stock       $ 100,000,000                          
Offering price       $ 100,000,000                          
Proceeds from issuance of common stock net of underwriting discounts and expenses                             $ 24,602,110    
Exchange Agreement [Member]                                  
Class of Stock [Line Items]                                  
Exercise price of warrants                                 $ 150
Warrants expiration date                                 Aug. 20, 2024
Warrants to purchase common stock                                 3,833
Engagement Letter [Member]                                  
Class of Stock [Line Items]                                  
Warrants to purchase common stock   18,412                              
Board of Directors [Member] | 2016 Equity Incentive Plan [Member]                                  
Class of Stock [Line Items]                                  
Maximum number of shares eligible to receive by employees                         83        
Number of options to purchase common stock                     83            
Exercise price of options                     $ 15,000            
Options vesting term                     4 years            
Percentage of vesting of options                     25.00%            
Board of Directors [Member] | 2016 Equity Incentive Plan [Member] | Maximum [Member]                                  
Class of Stock [Line Items]                                  
Number of shares issued                         83        
Board of Directors [Member] | 2018 Equity Incentive Plan [Member] | Maximum [Member]                                  
Class of Stock [Line Items]                                  
Number of shares issued                   625              
Placement Agent Warrants [Member]                                  
Class of Stock [Line Items]                                  
Number of warrants issued 10,000                       165     9  
Exercise price of warrants $ 7.5                       $ 1,500     $ 18,000  
Placement Agent Warrants One [Member]                                  
Class of Stock [Line Items]                                  
Number of warrants issued                         32        
Exercise price of warrants                         $ 18,000        
Placement Agent Warrants Two [Member]                                  
Class of Stock [Line Items]                                  
Number of warrants issued                         133        
Exercise price of warrants                         $ 1,500        
Class B Warrants [Member]                                  
Class of Stock [Line Items]                                  
Number of warrants issued                         177     177  
Exercise price of warrants                         $ 18,000        
Number of warrants outstanding                         177     177  
Series A Warrants and Series B Warrants [Member] | Investors [Member] | Exchange Agreement [Member]                                  
Class of Stock [Line Items]                                  
Warrants to purchase common stock                 283                
Proceeds from warrants exercise                 $ 2,172,680                
Stock issuance cost                 $ 159,958                
Series A Warrants and Series B Warrants One [Member] | Investors [Member] | Exchange Agreement [Member]                                  
Class of Stock [Line Items]                                  
Warrants to purchase common stock                 339                
Number of shares issued for exercise of warrants                 339                
Series A Warrants [Member]                                  
Class of Stock [Line Items]                                  
Number of warrants issued                               3,460  
Exercise price of warrants                           $ 5,505      
Number of warrants outstanding                         3,460        
Series A Warrant [Member]                                  
Class of Stock [Line Items]                                  
Number of warrants issued                         3,460        
Number of warrants outstanding                               3,460  
Warrants exercisable shares, description                           Each warrant expires on the fifth anniversary of the original issuance date.      
2020 Offering Warrants [Member]                                  
Class of Stock [Line Items]                                  
Number of warrants issued                         102,450     102,450  
Number of warrants outstanding                         102,450     102,450  
Warrants exercisable shares, description           the Company sold 138,000 warrants (each exercisable into 1 share of common stock for a total of 138,000 shares of common stock.)   the Company sold 329,667 warrants (each exercisable into 1/20th of a share of common stock for a total of 16,483 shares of common stock). In the June 2, 2020 public offering, the Company sold 138,000 warrants (each exercisable into 1 share of common stock for a total of 138,000 shares of common stock.)                  
Number of warrants sold           138,000   329,667                  
Number of warrants converted to common stock                         0        
Restricted Stock Units [Member] | 2018 Equity Incentive Plan [Member]                                  
Class of Stock [Line Items]                                  
Number of options to purchase common stock             144,110                    
Number of restricted stock units granted             350                    
2021 Offering Warrants [Member]                                  
Class of Stock [Line Items]                                  
Exercise price of warrants   $ 162.94                              
Number of warrants outstanding                         153,433        
Warrants to purchase common stock   1                              
Number of warrants sold   153,433                              
Number of warrants converted to common stock   18,412                              
Percentage of exercise price over offering price   125.00%                              
2021 Placement Agent Warrants [Member]                                  
Class of Stock [Line Items]                                  
Number of warrants issued                         153,433     18,412  
Number of warrants outstanding                               18,412  
Unregistered Warrants [Member]                                  
Class of Stock [Line Items]                                  
Exercise price of warrants $ 37.65                                
Warrants to purchase common stock 125,000                                
2022 Offering Warrants [Member]                                  
Class of Stock [Line Items]                                  
Number of warrants issued                         125,000        
Number of warrants outstanding                         125,000        
Warrants to purchase common stock 1                                
Number of warrants sold 125,000                                
Warrants and Rights Outstanding, Term 5 years                                
2022 Offering Warrants [Member] | Warrant [Member]                                  
Class of Stock [Line Items]                                  
Financial liabilities at fair value                         $ 2,646,135        
2022 Placement Agent Warrants [Member]                                  
Class of Stock [Line Items]                                  
Number of warrants issued 10,000                       10,000        
Exercise price of warrants $ 7.5                                
Number of warrants outstanding                         10,000        
2022 Placement Agent Warrants [Member] | Warrant [Member]                                  
Class of Stock [Line Items]                                  
Financial liabilities at fair value                         $ 2,242,620        
October 2016 Private Placement [Member] | Placement Agent Warrants [Member]                                  
Class of Stock [Line Items]                                  
Warrants expiration date                         Oct. 17, 2021        
August 2018 Financing [Member] | Placement Agent Warrants [Member]                                  
Class of Stock [Line Items]                                  
Warrants expiration date                         Sep. 04, 2023        
Series D Preferred Stock [Member]                                  
Class of Stock [Line Items]                                  
Preferred stock, shares authorized                         5,775     5,775  
Preferred stock par value                         $ 1,000     $ 1,000  
Series E Non Convertible Preferred Stock [Member]                                  
Class of Stock [Line Items]                                  
Preferred stock, shares authorized                         15        
Preferred stock par value                         $ 0.0001        
Stock issued during the period, value                         $ 1,000,000        
Series D Preferred Stock [Member]                                  
Class of Stock [Line Items]                                  
Preferred stock, shares authorized                               5,775  
Series E Preferred Stock [Member]                                  
Class of Stock [Line Items]                                  
Preferred stock, shares authorized                         15     15  
Preferred stock par value                         $ 0.0001     $ 0.0001  
Series E Preferred Stock [Member] | Institutional Investor [Member]                                  
Class of Stock [Line Items]                                  
Number of shares issued     9                            
Series F Preferred Stock [Member]                                  
Class of Stock [Line Items]                                  
Preferred stock, shares authorized                         2,500     0  
Preferred stock par value $ 0.0001                       $ 0.0001     $ 0.0001  
Stock issued during period stock split 2,500                                
Issuance of common stock upon conversion of preferred stock 83,334                                
Conversion price $ 30                                
Series G Preferred Stock [Member]                                  
Class of Stock [Line Items]                                  
Preferred stock, shares authorized                         2,500     0  
Preferred stock par value $ 0.0001                       $ 0.0001     $ 0.0001  
Stock issued during period stock split 2,500                                
Issuance of common stock upon conversion of preferred stock 83,334                                
Conversion price $ 30